Clear cell renal cell cancer (ccRCC) is a tumor of high malignancy, which can escape apoptosis.The tumor protein p53-inducible nuclear protein 2 (TP53INP2), known as an autophagy protein, is the essential part for autophagosome formation and sensitizes cells to apoptosis.Our study is aimed at exploring the role of TP53INP2 in ccRCC.We have identifi
Silvia Coretti,1 Federica Romano,1 Valentina Orlando,2 Paola Codella,1 Sabrina Prete,1 Eugenio Di Brino,1 Matteo Ruggeri1 1Post-Graduate School of Economics and Management (ALTEMS), Università Cattolica del Sacro Cuore, Rome, Italy; 2Center of Pharmacoeconomics (CIRFF), Department of Pharmacy, Federico II University, Naples, Italy Background
Abstract Over the last few years, cancer immunotherapy experienced tremendous developments and it is nowadays considered a promising strategy against many types of cancer.However, the exclusion of lymphocytes from the tumor nest is a common phenomenon that limits the efficiency of immunotherapy in solid tumors.Despite several mechanisms proposed du
Summary Introduction: The bone-anchored hearing aid (BAHA) is a bone conduction hearing device that transmits sound directly into the inner ear.It is mainly used in patients with conductive hearing loss associated with aural atresia, but it is also used in those with mixed and sensorineural hearing loss.Goals: To review the main indications for BAH
In classical Fourier optics, an optical sophie allport bee curtains imaging system is regarded as a linear space-invariant system, which is only an approximation.Especially in digital holography, the space-variance effect has a great impact on the image quality and cannot be ignored.Therefore, it is comprehensively investigated in this article.Theo